, Volume 46, Issue 3, pp 682-683
Date: 22 Oct 2013

Small cell carcinoma of the thyroid gland with a solid brain metastasis detected by F-18-FDG PET/CT

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access
This is an excerpt from the content

A 77-year-old man underwent fine needle aspiration biopsy of a 3.5 cm nodule of the right thyroid lobe. Cytology showed small cells with scant cytoplasm; on immunocytochemistry, the cells showed high proliferative activity and cytoplasmic expression for neuroendocrine marker synaptophysin. These findings were suggestive for a small cell carcinoma of the thyroid gland. Therefore, the patient underwent fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (F-18-FDG PET/CT) for staging. PET/CT showed an area of increased F-18-FDG uptake corresponding to the right thyroid nodule (Fig. 1a, b). Furthermore, an area of increased radiopharmaceutical uptake was detected in the brain, corresponding to a lesion located in the left parietal lobe on low-dose CT (Fig. 1a, c). Biopsy of the brain lesion was suggestive for small cell carcinoma. The final diagnosis based on pathology and F-18-FDG PET/CT findings was small cell carcinoma of the thyroid gland with brain metastas