Endocrine

, Volume 43, Issue 1, pp 41–50

Continuous glucose monitoring in type 1 diabetes

  • Nelly Mauras
  • Larry Fox
  • Kimberly Englert
  • Roy W. Beck
Review

DOI: 10.1007/s12020-012-9765-1

Cite this article as:
Mauras, N., Fox, L., Englert, K. et al. Endocrine (2013) 43: 41. doi:10.1007/s12020-012-9765-1

Abstract

Continuous glucose monitors (CGM), devices that can measure interstitial glucose in “real time,” have become widely available particularly for use in patients with diabetes, and their accuracy and ease of use have greatly improved over the last decade. A number of large and well-controlled clinical trials have firmly established their usefulness in improving metabolic control (as measured by HbA1C) and decreasing time spent in hypoglycemia in adults; however, data have been less robust proving benefit in children and adolescents. Benefits are clearly linked to near-continuous wear. Insulin dosing algorithms based on CGM glucose trends have proven useful in dissecting the large volume of data generated daily by these devices, although these are imperfect tools, particularly in children. The technology is likely to be most useful when integrated with insulin pump delivery systems (sensor augmented). In this review, we concentrate on the analysis of published results of the largest trials in adults and children, including the very young, with diabetes.

Keywords

Continuous glucose sensorsAdolescentsChildrenDiabetes controlQuality of life

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Nelly Mauras
    • 1
  • Larry Fox
    • 1
  • Kimberly Englert
    • 1
  • Roy W. Beck
    • 2
  1. 1.Nemours Children’s ClinicJacksonvilleUSA
  2. 2.Jaeb Center for Health ResearchTampaUSA