Endocrine

, Volume 37, Issue 1, pp 1–5

Carcinoid tumor of the thymus associated with Cushing′s syndrome and dysgeusia: case report and review of the literature

  • Cristina Claret
  • Juan J. Chillarón
  • Juana A. Flores
  • David Benaiges
  • Rafael Aguiló
  • Mar García
  • Guadalupe Aguilar
  • Alberto Goday
  • Juan F. Cano-Pérez
Case Report and Review

DOI: 10.1007/s12020-009-9249-0

Cite this article as:
Claret, C., Chillarón, J.J., Flores, J.A. et al. Endocr (2010) 37: 1. doi:10.1007/s12020-009-9249-0

Abstract

A 30-year-old man was hospitalized with edema, polyuria, and abnormalities in taste. ACTH and cortisol levels at admission were markedly elevated, even after attempted suppression with 8 mg dexamethasone. A thoracic–abdominal CT revealed an anterior mediastinal lesion and hyperplasia of both adrenal glands. After excision of the mediastinal mass, which confirmed the presence of a carcinoid thymic tumor, the patient became totally asymptomatic, with normal ACTH and cortisol levels. A carcinoid thymic tumor has a poor prognosis, especially when it is associated with Cushing’s syndrome. Most patients will present recidivism or metastasis within 5 years after surgery. However, the low number of cases available for analysis makes it difficult to establish optimum therapeutic approaches.

Keywords

CarcinoidNeuroendocrine tumorsThymusCushing′s syndrome

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Cristina Claret
    • 1
    • 5
  • Juan J. Chillarón
    • 1
    • 5
  • Juana A. Flores
    • 1
    • 5
  • David Benaiges
    • 1
    • 5
  • Rafael Aguiló
    • 2
  • Mar García
    • 3
  • Guadalupe Aguilar
    • 4
  • Alberto Goday
    • 1
    • 5
  • Juan F. Cano-Pérez
    • 1
    • 5
  1. 1.Department of EndocrinologyHospital Universitari del MarBarcelonaSpain
  2. 2.Department of Thoracic SurgeryHospital Universitari del MarBarcelonaSpain
  3. 3.Department of PathologyHospital Universitari del MarBarcelonaSpain
  4. 4.Department of Diagnostic RadiologyHospital Universitari del MarBarcelonaSpain
  5. 5.Department of MedicineUniversitat Autònoma de BarcelonaBarcelonaSpain