Comprehensive Therapy

, Volume 33, Issue 4, pp 174–183

Aortic Stenosis

Original Article

DOI: 10.1007/s12019-007-8021-8

Cite this article as:
Aronow, W.S. Compr Ther (2007) 33: 174. doi:10.1007/s12019-007-8021-8

Patients with aortic stenosis (AS) have an increased prevalence of coronary risk factors, coronary artery disease, and other atherosclerotic vascular disease and an increased incidence of coronary events and death. Statins may reduce the progression of AS. Angina pectoris, syncope or near syncope, and heart failure are the three classic manifestations of severe AS. Prolonged duration and late peaking of an aortic systolic ejection murmur best differentiate severe AS from mild AS on physical examination. Doppler echocardiography is used to diagnose the presence and severity of AS. Once symptoms develop, aortic valve replacement (AVR) should be performed in patients with severe or moderate AS. Warfarin should be administered indefinitely after AVR in patients with a mechanical aortic valve and in patients with a bioprosthetic aortic valve who have either atrial fibrillation, prior thromboembolism, left ventricular systolic dysfunction, or a hypercoagulable condition. Patients with a bioprosthetic aortic valve without any of these four risk factors should be treated with aspirin 75–100 mg daily.

Copyright information

© The American Society of Contempary Medicine and Surgery 2007

Authors and Affiliations

  1. 1.Depatment of Medicine, Divisions of Cardiology, Geriatrics, and Pulmonary/Critical CareNew York Medical CollegeValhallaUSA