Comprehensive Therapy

, Volume 33, Issue 2, pp 99–103

Conjunctival Pigmentation in Stevens–Johnson Syndrome

  • Graciana Fuentes-Páez
  • Maria C. Mendez
  • Javier Montañez
  • Jose M. Herreras
  • Maria A. Saornil
  • Margarita Calonge
Case Report

DOI: 10.1007/s12019-007-8009-4

Cite this article as:
Fuentes-Páez, G., Mendez, M.C., Montañez, J. et al. Compr Ther (2007) 33: 99. doi:10.1007/s12019-007-8009-4
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Abstract

We report a 29-year-old white female with conjunctival pigmentation after a Stevens–Johnson syndrome (SJS) episode triggered by sulfasalazine. The patient developed bilateral tarsal and forniceal conjunctiva and black pigmentation. Diagnostic biopsy showed stromal monocyte infiltration consistent with chronic phase SJS and conjunctival pigment of melanic origin and not due to drug deposition. Treatment with topical steroids and unpreserved artificial tears resulted in improvement of clinical symptoms; however, pigmentation was unchanged after 2 years.

Keywords

Conjunctival pigmentationErythema multiformeMelaninStevens–Johnson syndromeSulfasalazine

Copyright information

© The American Society of Contempary Medicine and Surgery 2007

Authors and Affiliations

  • Graciana Fuentes-Páez
    • 1
  • Maria C. Mendez
    • 1
  • Javier Montañez
    • 2
  • Jose M. Herreras
    • 1
  • Maria A. Saornil
    • 1
  • Margarita Calonge
    • 1
  1. 1.IOBA (Institute of Ophthalmobiology)University of ValladolidValladolidSpain
  2. 2.Hospital Son DuretaPalma de MallorcaSpain