Stem Cell Reviews

, Volume 3, Issue 4, pp 265–269

Cell Tracing Techniques in Stem Cell Transplantation

  • Li Yan
  • Ying Han
  • Yuanlong He
  • Huahong Xie
  • Jingmei Liu
  • Lina Zhao
  • Jingbo Wang
  • Liuchun Gao
  • Daiming Fan
Article

DOI: 10.1007/s12015-007-9004-y

Cite this article as:
Yan, L., Han, Y., He, Y. et al. Stem Cell Rev (2007) 3: 265. doi:10.1007/s12015-007-9004-y

Abstract

Pluripotent stem cells have shown great therapeutic promise because of their natural capacity to regenerate damaged tissue. Likewise, autologous stem cells or genetically modified stem cells have already been successfully applied in animal or clinical experimental studies including cardiopathy, diabetic disease, system lupus erythema, pancreatic disease, and liver disease. In these studies regarding stem cell transplants in different diseases, identifying the location of implanted cells and distinguishing them from endogenous cells is the first and most important step. Moreover, different tracing techniques were applied in different studies for their different sensitivity, dynamic range, convenience and reliability of their assays. Therefore, we will here review different tracing techniques and their applications in stem cell transplants, including both experiment studies and preclinical trials.

Keywords

Stem cellsTransplantsTracing techniques

Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  • Li Yan
    • 1
    • 2
  • Ying Han
    • 1
  • Yuanlong He
    • 1
  • Huahong Xie
    • 1
  • Jingmei Liu
    • 1
  • Lina Zhao
    • 1
  • Jingbo Wang
    • 1
  • Liuchun Gao
    • 1
  • Daiming Fan
    • 1
  1. 1.Department of GastroenterologyXijing Hospital, Fourth Military Medical UniversityXi’anChina
  2. 2.Department of Gastroenterology401 Hospital of PLAQingdaoChina