, Volume 153, Issue 1-3, pp 319-328,
Open Access This content is freely available online to anyone, anywhere at any time.
Date: 11 May 2013

Influence of Vanadium–organic Ligands Treatment on Selected Metal Levels in Kidneys of STZ Rats


The objective of the study was to investigate the effects of five organic vanadium complexes supplement and a small dose of insulin injection on V, Fe, Cu, Zn, Mn, Ca, and K level in the streptozotocin diabetic rat’s kidney during a 5-week treatment with the tested complexes. In all groups of animals, metal level in the lyophilized kidney organs was investigated by means of the proton induced X-ray emission method. Tissue vanadium level was naturally higher in vanadium-treated rats. The maximum level of vanadium was observed in the kidney ( \( {x_{\text mean}} =16.6\ \upmu \mathrm{g}/\left. \mathrm{g} \right) \) . The influence of vanadium administration on other metal level in rat’s tissue was also investigated. Spectacular influence of vanadium action was observed on copper and zinc level in examined tissue.