Applied Biochemistry and Biotechnology

, Volume 174, Issue 3, pp 1010–1020

Sensitive and Reliable Ascorbic Acid Sensing by Lanthanum Oxide/Reduced Graphene Oxide Nanocomposite


DOI: 10.1007/s12010-014-0986-z

Cite this article as:
Mogha, N.K., Sahu, V., Sharma, M. et al. Appl Biochem Biotechnol (2014) 174: 1010. doi:10.1007/s12010-014-0986-z


A simple strategy for the detection and estimation of ascorbic acid (AA), using lanthanum oxide–reduced graphene oxide nanocomposite (LO/RGO) on indium tin oxide (ITO) substrate, is reported. LO/RGO displays high catalytic activity toward the oxidation of AA, and the synergism between lanthanum oxide and reduced graphene oxide was attributed to the successful and efficient detection. Detection mechanism and sensing efficacy of LO/RGO nanocomposite are investigated by electrochemical techniques. Chronoamperometric results under optimal conditions show a linear response range from 14 to 100 μM for AA detection. Commercially available vitamin C tablets were also analyzed using the proposed LO/RGO sensor, and the remarkable recovery percentage (97.64–99.7) shows the potential application in AA detection.


Lanthanum oxide Reduced graphene nanocomposite Ascorbic acid Electrochemical sensor 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of ChemistryUniversity of DelhiDelhiIndia
  2. 2.Dr. B.R. Ambedkar Center for Biomedical ResearchUniversity of DelhiDelhiIndia