Applied Biochemistry and Biotechnology

, Volume 160, Issue 8, pp 2401–2414

α-Amylase: An Ideal Representative of Thermostable Enzymes


DOI: 10.1007/s12010-009-8735-4

Cite this article as:
Prakash, O. & Jaiswal, N. Appl Biochem Biotechnol (2010) 160: 2401. doi:10.1007/s12010-009-8735-4


The conditions prevailing in the industrial applications in which enzymes are used are rather extreme, especially with respect to temperature and pH. Therefore, there is a continuing demand to improve the stability of enzymes and to meet the requirements set by specific applications. In this respect, thermostable enzymes have been proposed to be industrially relevant. In this review, α-amylase, a well-established representative of thermostable enzymes, providing an attractive model for the investigation of the structural basis of thermostability of proteins, has been discussed.


α-AmylaseThermostabilityStructural flexibilityRigidityUnfolding state

Copyright information

© Humana Press 2009

Authors and Affiliations

  1. 1.Department of Biochemistry, Faculty of ScienceBanaras Hindu UniversityVaranasiIndia