, Volume 4, Issue 3, pp 213-224

Human immunodeficiency virus (HIV) in children

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Opinion statement

Recent advances in antiretroviral treatment have changed the landscape of pediatric HIV—not only has perinatal treatment markedly diminished HIV transmission rates, but highly active antiretroviral treatments (HAART) have, with few exceptions, transformed HIV into a chronic nonfatal disorder. Antiretroviral therapies are complex and fraught with potential for side effects. The neurologist involved with HIV-infected children should have a firm grasp on the different therapeutic agents used among infected children, especially as regards drug metabolism and indications for treatment.