Current Treatment Options in Cardiovascular Medicine

, Volume 8, Issue 2, pp 153-165

First online:


  • Mark D. P. DavisAffiliated withDepartment of Dermatology and the Gonda Vascular Center, Mayo Clinic and Mayo Foundation
  • , Thom Rooke

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Opinion statement

No treatment is consistently effective in the management of patients with erythromelalgia. There is a dearth of adequate studies examining the response of erythromelalgia to treatment. Most recommendations are suggested based on case reports, small case series, and anecdotal reports. The management of erythromelalgia is difficult and frequently involves a multidisciplinary approach. An approach to management of individuals with erythromelalgia includes patient education, learning to avoid episodes, relieving discomfort of the episodes, controlling secondary and underlying factors, and use of drugs used to control erythromelalgia.