Current Urology Reports

, 15:387

Role of Multiparametric Magnetic Resonance Imaging in the Diagnosis of Prostate Cancer

  • Soroush Rais-Bahrami
  • Baris Turkbey
  • Kinzya B. Grant
  • Peter A. Pinto
  • Peter L. Choyke
New Imaging Techniques (A Atala and A Rastinehad, Section Editors)

DOI: 10.1007/s11934-013-0387-9

Cite this article as:
Rais-Bahrami, S., Turkbey, B., Grant, K.B. et al. Curr Urol Rep (2014) 15: 387. doi:10.1007/s11934-013-0387-9
Part of the following topical collections:
  1. Topical Collection on New Imaging Techniques

Abstract

Prostate cancer is the most common solid-organ malignancy among American men. It is currently most commonly diagnosed on random systematic biopsies prompted by elevated serum PSA levels. Multi-parametric MRI (MP-MRI) of the prostate has emerged as an anatomic and functional imaging modality, which offers accurate detection, localization and staging of prostate cancer. Recently, MP-MRI has gained an increasing role in guiding biopsies to sites of abnormality and in monitoring patients on active surveillance. Here, we discuss the historical development, current role, and potential future directions of MP-MRI in the diagnosis of prostate cancer.

Keywords

Cancer DetectionMagnetic Resonance ImagingProstate BiopsyCancer Imaging

Abbreviations

(bGS)

Biopsy Gleason Score

(B-MRI)

Biparametric MRI

(DWI)

Diffusion Weighted Imaging

(DRE)

Digital Rectal Examination

(MRI)

Magnetic Resonance Imaging

(MR/US)

Magnetic Resonance/Ultrasound

(MP-MRI)

Multiparametric MRI

(NPV)

Negative Predictive Value

(PPV)

Positive Predictive Value

(PCa)

Prostate Cancer

(PSA)

Prostate Specific Antigen

(PSAD)

PSA Density

(SPL)

Screen Positive Lesions

(T2W)

T2 Weighted

Copyright information

© Springer Science+Business Media New York (outside the USA) 2014

Authors and Affiliations

  • Soroush Rais-Bahrami
    • 1
  • Baris Turkbey
    • 2
  • Kinzya B. Grant
    • 2
  • Peter A. Pinto
    • 1
    • 3
  • Peter L. Choyke
    • 2
  1. 1.Urologic Oncology BranchNational Cancer Institute, National Institutes of HealthBethesdaUSA
  2. 2.Molecular Imaging ProgramNational Cancer Institute, National Institutes of HealthBethesdaUSA
  3. 3.Center for Interventional OncologyNational Cancer Institute, National Institutes of HealthBethesdaUSA