Practical Use of the New American Urological Association Interstitial Cystitis Guidelines Authors
Voiding Dysfunction and Lower Urinary Tract Symptoms (GH Badlani and HB Goldman, Section Editors)
First Online: 25 July 2012 DOI:
Cite this article as: Quillin, R.B. & Erickson, D.R. Curr Urol Rep (2012) 13: 394. doi:10.1007/s11934-012-0263-z Abstract
The American Urological Association recently developed guidelines to assist clinicians who evaluate and treat interstitial cystitis/bladder pain syndrome. Knowledge in this area continues to advance, and some of the guideline statements differ from what clinicians may have been previously taught. This review includes the 27 guideline statements, which address both evaluation and treatment. This review lists the guideline statements and, when applicable, comments on their practical implementation and the most recent research. Practical information includes the following: key questions that help in the differential diagnosis, when to perform cystoscopy and urodynamics, how to recognize and treat Hunner lesions, useful practical resources for patients and clinicians, information on elimination diet and stress management, initial selection of oral and intravesical medications, and description of advanced treatment options (limited to dedicated, experienced clinicians).
Keywords Interstitial cystitis Diagnosis Therapy Painful bladder syndrome Guidelines References Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance
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This is the AUA Guideline manuscript, on which this article is based. The document, algorithm, and slide presentation are available on the AUA Web site
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In this single-dose trial, the lidocaine cocktail was more effective than placebo
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After five daily doses, alkalinized lidocaine was more effective than placebo
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This three-arm trial included alkalinized lidocaine alone, hyaluronic acid alone, or both together. At week 4, all groups had approximately a 30 % response rate. At week 24, response rates were about 68 % for the two hyaluronic acid groups but only about 8 % for alkalinized lidocaine alone.
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This is a superb comprehensive chapter
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© Springer Science+Business Media, LLC 2012