Current Rheumatology Reports

, Volume 11, Issue 6, pp 402–409

Systemic vasculitis in childhood


DOI: 10.1007/s11926-009-0059-4

Cite this article as:
Gedalia, A. & Cuchacovich, R. Curr Rheumatol Rep (2009) 11: 402. doi:10.1007/s11926-009-0059-4


Systemic vasculitis is a group of disorders with multiorgan involvement. These disorders have diverse clinical manifestations associated with significant morbidity and mortality. The most common vasculitides in children—Henoch-Schönlein purpura and Kawasaki disease—are self-limiting conditions. The lifelong and chronic vasculitides (eg, giant cell arteritis, Wegener’s granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome, polyarteritis nodosa, and Takayasu arteritis) are rarely seen in children. Therefore, the outcome in general is more favorable in children. This article offers an overview of the epidemiologic, etiologic, pathophysiologic, and clinical features of vasculitis in children, with emphasis on common conditions.

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of PediatricsLouisiana State University Health Sciences Center, Children’s HospitalNew OrleansUSA