Current Psychiatry Reports

, 15:426

Use of Antipsychotic Medications in Pediatric Populations: What do the Data Say?

  • Robert B. Penfold
  • Christine Stewart
  • Enid M. Hunkeler
  • Jeanne M. Madden
  • Janet R. Cummings
  • Ashli A. Owen-Smith
  • Rebecca C. Rossom
  • Christine Y. Lu
  • Frances L. Lynch
  • Beth E. Waitzfelder
  • Karen A. Coleman
  • Brian K. Ahmedani
  • Arne L. Beck
  • John E. Zeber
  • Gregory E. Simon
Schizophrenia and Other Psychotic Disorders (SJ Siegel, Section Editor)

DOI: 10.1007/s11920-013-0426-8

Cite this article as:
Penfold, R.B., Stewart, C., Hunkeler, E.M. et al. Curr Psychiatry Rep (2013) 15: 426. doi:10.1007/s11920-013-0426-8
Part of the following topical collections:
  1. Topical Collection on Schizophrenia and Other Psychotic Disorders

Abstract

Recent reports of antipsychotic medication use in pediatric populations describe large increases in rates of use. Much interest in the increasing use has focused on potentially inappropriate prescribing for non-Food and Drug Administration-approved uses and use amongst youth with no mental health diagnosis. Different studies of antipsychotic use have used different time periods, geographic and insurance populations of youth, and aggregations of diagnoses. We review recent estimates of use and comment on the similarities and dissimilarities in rates of use. We also report new data obtained on 11 health maintenance organizations that are members of the Mental Health Research Network in order to update and extend the knowledge base on use by diagnostic indication. Results indicate that most use in pediatric populations is for disruptive behaviors and not psychotic disorders. Differences in estimates are likely a function of differences in methodology; however, there is remarkable consistency in estimates of use by diagnosis.

Keywords

AntipsychoticsChildrenAdolescentsMedicaidMental Health Research NetworkOff-labelMarketScanIMS HealthNAMCSNDTINCS-A

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Robert B. Penfold
    • 1
    • 2
  • Christine Stewart
    • 1
  • Enid M. Hunkeler
    • 3
  • Jeanne M. Madden
    • 4
    • 5
  • Janet R. Cummings
    • 6
  • Ashli A. Owen-Smith
    • 7
  • Rebecca C. Rossom
    • 8
    • 9
  • Christine Y. Lu
    • 4
    • 5
  • Frances L. Lynch
    • 10
  • Beth E. Waitzfelder
    • 11
  • Karen A. Coleman
    • 12
  • Brian K. Ahmedani
    • 13
  • Arne L. Beck
    • 14
  • John E. Zeber
    • 15
  • Gregory E. Simon
    • 1
    • 16
  1. 1.Group Health Research InstituteSeattleUSA
  2. 2.Department of Health Services ResearchUniversity of WashingtonSeattleUSA
  3. 3.Kaiser Permanente Division of Research, Northern CaliforniaOaklandUSA
  4. 4.Harvard Pilgrim Health Care Research InstituteBostonUSA
  5. 5.Department of Population MedicineHarvard Medical SchoolBostonUSA
  6. 6.Department of Health Policy and Management, Rollins School of Public HealthEmory UniversityAtlantaUSA
  7. 7.Kaiser Permanente Center for Health Research SoutheastAtlantaUSA
  8. 8.Health Partners Institute for Education and ResearchBloomingtonUSA
  9. 9.Department of PsychiatryUniversity of MinnesotaMinneapolisUSA
  10. 10.Kaiser Permanente Center for Health Research, NorthwestPortlandUSA
  11. 11.Kaiser Permanente Center for Health Research, HawaiiHonoluluUSA
  12. 12.Kaiser Permanente Center for Health Research, Southern CaliforniaPasadenaUSA
  13. 13.Henry Ford Health SystemDetroitUSA
  14. 14.Kaiser Permanente Institute for Health Research, ColoradoDenverUSA
  15. 15.Center for Applied Health Research, Scott and White Healthcare and Central Texas VATempleUSA
  16. 16.Department of PsychiatryUniversity of WashingtonSeattleUSA