Current Psychiatry Reports

, Volume 12, Issue 2, pp 88–95

From TADS and SOFTADS to TORDIA and Beyond: What’s New in the Treatment of Adolescent Depression?


  • Zheya Jenny Yu
    • Hall-Mercer MH/MR Center, Pennsylvania HospitalUniversity of Pennsylvania Health System
    • University of Nebraska Medical Center
  • Ronald A. Weller
    • Department of PsychiatryUniversity of Pennsylvania
  • Mira Mooreville
    • University of Michigan
  • Elizabeth B. Weller
    • The Children’s Hospital of PhiladelphiaUniversity of Pennsylvania

DOI: 10.1007/s11920-010-0094-x

Cite this article as:
Yu, Z.J., Kratochvil, C.J., Weller, R.A. et al. Curr Psychiatry Rep (2010) 12: 88. doi:10.1007/s11920-010-0094-x


Major depressive disorder in adolescents is associated with significant morbidity and mortality. Major advances have been made in recent years in the treatment of adolescent depression, with promising outcomes. However, limitations of currently available treatments have prompted attempts to better understand pediatric depression from a broader perspective and to develop more effective treatment strategies in the future.


AdolescentDepressionPharmacotherapyCognitive-behavioral therapy

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© Springer Science+Business Media, LLC 2010