Why Does Sleep Stop Migraine?

Migraine (R Cowan, Section Editor)

DOI: 10.1007/s11916-013-0369-0

Cite this article as:
Bigal, M.E. & Hargreaves, R.J. Curr Pain Headache Rep (2013) 17: 369. doi:10.1007/s11916-013-0369-0
Part of the following topical collections:
  1. Topical Collection on Migraine


The relationship between sleep and migraine headaches is complex. Changes in sleep patterns can trigger migraine attacks, and sleep disorders may be associated with increased migraine frequency. Furthermore, migraine patients and their doctors very consistently report that sleep relieves already established migraine attacks. Herein we will try to answer the question, “Why does sleep stop migraine?” Since evidence for this relationship is largely based on empirical clinical observation, we will not provide a clinical review of the association. Instead, we will focus on the pathophysiology of migraine attacks and its intersections with sleep biology.


Migraine Sleep Trigger factors Migraine cessation 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Labrys Biologics Inc.San MateoUSA
  2. 2.Preclinical ResearchMerck Inc.Whitehouse StationUSA