Current Pain and Headache Reports

, Volume 8, Issue 6, pp 468-475

An expansion of Simons’ integrated hypothesis of trigger point formation

  • Robert D. GerwinAffiliated withJohns Hopkins University, Pain and Rehabilitation Medicine
  • , Jan Dommerholt
  • , Jay P. Shah

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Simons’ integrated hypothesis proposed a model of trigger point (TrP) activation to explain known TrP phenomena, particularly endplate noise. We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology.