Current Pain and Headache Reports

, Volume 8, Issue 6, pp 468–475

An expansion of Simons’ integrated hypothesis of trigger point formation

  • Robert D. Gerwin
  • Jan Dommerholt
  • Jay P. Shah

DOI: 10.1007/s11916-004-0069-x

Cite this article as:
Gerwin, R.D., Dommerholt, J. & Shah, J.P. Current Science Inc (2004) 8: 468. doi:10.1007/s11916-004-0069-x


Simons’ integrated hypothesis proposed a model of trigger point (TrP) activation to explain known TrP phenomena, particularly endplate noise. We propose an expansion of this hypothesis to account for new experimental data and established muscle pathophysiology.

Copyright information

© Current Science Inc 2004

Authors and Affiliations

  • Robert D. Gerwin
    • 1
  • Jan Dommerholt
  • Jay P. Shah
  1. 1.Johns Hopkins University, Pain and Rehabilitation MedicineBethesdaUSA