Ethical considerations in cluster headache research
- Cite this article as:
- Tepper, S.J., Rapoport, A.M. & Sheftell, F.D. Current Science Inc (2002) 6: 47. doi:10.1007/s11916-002-0023-8
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Cluster headache is the most painful of the primary headache disorders and elucidating pathophysiology and treatment for this disorder is crucial. There is justification for studying attacks untreated, and even for precipitating these attacks. Placebo-controlled studies should only be undertaken for regulatory purposes; otherwise, active control should be used.