Current Pain and Headache Reports

, Volume 6, Issue 1, pp 47–51

Ethical considerations in cluster headache research


  • Stewart J. Tepper
    • The New England Center for Headache
  • Alan M. Rapoport
  • Fred D. Sheftell

DOI: 10.1007/s11916-002-0023-8

Cite this article as:
Tepper, S.J., Rapoport, A.M. & Sheftell, F.D. Current Science Inc (2002) 6: 47. doi:10.1007/s11916-002-0023-8


Cluster headache is the most painful of the primary headache disorders and elucidating pathophysiology and treatment for this disorder is crucial. There is justification for studying attacks untreated, and even for precipitating these attacks. Placebo-controlled studies should only be undertaken for regulatory purposes; otherwise, active control should be used.

Copyright information

© Current Science Inc 2002