Current Osteoporosis Reports

, Volume 11, Issue 4, pp 286–298

Idiopathic Osteoporosis in Men

Epidemiology and Pathophysiology (RA Adler, Section Editor)

DOI: 10.1007/s11914-013-0164-1

Cite this article as:
Gennari, L. & Bilezikian, J.P. Curr Osteoporos Rep (2013) 11: 286. doi:10.1007/s11914-013-0164-1


Over the last decade, the increasingly significant problem of osteoporosis in men has begun to receive much more attention than in the past. In particular, recent observations from large scale population studies in males led to an advance in the understanding of morphologic basis of growth, maintenance and loss of bone in men, as well as new insights about the pathophysiology and treatment of this disorder. While fracture risk consistently increases after age 65 in men (with up to 50 % of cases due to secondary etiologies), osteoporosis and fractures may also occur in young or middle aged males in the absence of an identifiable etiology. For this category (so called idiopathic osteoporosis), there are still major gaps in knowledge, particularly concerning the etiology and the clinical management. This article provides a summary of recent developments in the acquisition and maintenance of bone strength in men, as well as new insights about the pathogenesis, diagnosis, and treatment of idiopathic osteoporosis.


Male osteoporosisIdiopathic osteoporosisPathogenesis of male osteoporosisDiagnosis of osteoporosis in menTreatment of osteoporosis in men

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Medicine, Surgery and NeurosciencesUniversity of SienaSienaItaly
  2. 2.Metabolic Bone Diseases Unit, Department of Medicine, College of Physicians and SurgeonsColumbia UniversityNew YorkUSA