Epidemiology and Pathophysiology (Mone Zaidi and Jeffrey I. Mechanick, Section Editors)

Current Osteoporosis Reports

, 9:243

First online:

Vitamin D in the Persian Gulf: Integrative Physiology and Socioeconomic Factors

  • Jessica FieldsAffiliated withDivision of Endocrinology, Diabetes, and Bone Disease, Mount Sinai School of Medicine
  • , Nishant J. TrivediAffiliated withDivision of Endocrinology, Diabetes, and Bone Disease, Mount Sinai School of Medicine
  • , Edward HortonAffiliated withJoslin Institute, Harvard Medical School
  • , Jeffrey I. MechanickAffiliated withDivision of Endocrinology, Diabetes, and Bone Disease, Mount Sinai School of Medicine Email author 

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access

Abstract

Countries of the Persian Gulf region—Bahrain, Iran, Iraq, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates—have become increasingly modernized, resulting in a transformation of lifestyle based on technology, sedentary activity, lack of sunlight, and unhealthy dietary patterns. These factors have led to a higher prevalence not only of vitamin D undernutrition, but also chronic obesity, insulin resistance, prediabetes, and type 2 diabetes. This review explores the integrative physiologic effects of vitamin D with socioeconomic factors and propose a hypothesis-driven model for their contributions to obesity and diabetes in the Persian Gulf. Further research into these interactions may ultimately lead to novel preventive strategies and therapies for metabolic disorders in this geographic region.

Keywords

Vitamin D Obesity Osteoporosis Diabetes Metabolic syndrome Persian Gulf region