Current Oncology Reports

, Volume 13, Issue 3, pp 157–167

Update: Modern Approaches to the Treatment of Localized Esophageal Cancer

  • James Welsh
  • Arya Amini
  • Anna Likhacheva
  • Jeremy Erasmus J.
  • Daniel Gomez
  • Marta Davila
  • Reza J. Mehran
  • Ritsuko Komaki
  • Zhongxing Liao
  • Wayne L. Hofstetter
  • Jeffrey Lee H.
  • Manoop S. Bhutani
  • Jaffer A. Ajani
Article

DOI: 10.1007/s11912-011-0158-z

Cite this article as:
Welsh, J., Amini, A., Likhacheva, A. et al. Curr Oncol Rep (2011) 13: 157. doi:10.1007/s11912-011-0158-z

Abstract

The optimal treatment strategy for esophageal cancer continues to be a topic of debate. Improvements in chemotherapy drugs, surgical techniques, and radiotherapy planning and delivery have led to the design of treatment approaches that are specific to both the stage of the tumor and the overall performance status of the patient. Surgery continues to be the standard treatment option for localized disease, but multimodality treatments that include radiation and chemotherapy with surgery are increasingly used. The next few years will continue to see improvements in radiation techniques, especially proton beam treatment; the development of additional minimally invasive surgical approaches to minimize postoperative side effects; and the discovery of molecular biomarkers to help specifically target treatment of esophageal cancer in individual patients.

Keywords

Esophageal cancer Diagnosis Minimally invasive treatments Chemoradiation Intensity-modulated radiation therapy Photon therapy Proton beam therapy 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • James Welsh
    • 1
  • Arya Amini
    • 2
  • Anna Likhacheva
    • 1
  • Jeremy Erasmus J.
    • 3
  • Daniel Gomez
    • 4
  • Marta Davila
    • 5
  • Reza J. Mehran
    • 6
  • Ritsuko Komaki
    • 1
  • Zhongxing Liao
    • 1
  • Wayne L. Hofstetter
    • 6
  • Jeffrey Lee H.
    • 5
  • Manoop S. Bhutani
    • 5
  • Jaffer A. Ajani
    • 7
  1. 1.Division of Radiation Oncology, Unit 97The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  2. 2.University of California, IrvineIrvineUSA
  3. 3.Department of Diagnostic Radiology, Unit 1478The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  4. 4.Department of Radiation Oncology, Unit 1150The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  5. 5.Department of Gastroenterology, Hepatology, and Nutrition, Unit 1466The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  6. 6.Department of Thoracic and Cardiovascular Surgery, Unit 1489The University of Texas M.D. Anderson Cancer CenterHoustonUSA
  7. 7.Department of Gastrointestinal Medical Oncology, Unit 426The University of Texas M.D. Anderson Cancer CenterHoustonUSA