Current Oncology Reports

, Volume 9, Issue 2, pp 89–95

The platelet-derived growth factor receptor as a therapeutic target


DOI: 10.1007/s11912-007-0003-6

Cite this article as:
Lewis, N.L. Curr Oncol Rep (2007) 9: 89. doi:10.1007/s11912-007-0003-6


Several small molecule tyrosine kinase inhibitors that block the epidermal growth factor receptor and vascular endothelial growth factor receptor function are among the many recently developed targeted anticancer therapeutic agents. Increasing evidence indicates that inhibition of other tumor stromal targets could provide additional and possibly synergistic antitumor effects. This article focuses on the platelet-derived growth factor receptor as one such potential target.

Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  1. 1.Fox Chase Cancer CenterPhiladelphiaUSA