Misdiagnosis of Multiple Sclerosis: Frequency, Causes, Effects, and Prevention

Demyelinating Disorders (DN Bourdette and V Yadav, Section Editors)

DOI: 10.1007/s11910-013-0403-y

Cite this article as:
Solomon, A.J. & Weinshenker, B.G. Curr Neurol Neurosci Rep (2013) 13: 403. doi:10.1007/s11910-013-0403-y
Part of the following topical collections:
  1. Topical Collection on Demyelinating Disorders


A diagnosis of multiple sclerosis is heavily influenced by clinical judgment. Misdiagnosis of multiple sclerosis is common and has important consequences for patients and the cost of healthcare. Although rigorous data about the frequency and causes of misdiagnosis are lacking, misinterpretation and misapplication of clinical and radiographic diagnostic criteria and terminology are likely important factors. Appropriate and stringent application of diagnostic criteria and continued vigilance for “red flags” suggesting alternative diagnoses are strategies critical for prevention of misdiagnosis.


Multiple sclerosis Diagnosis Misdiagnosis Mimickers Diagnostic Criteria Medical error Frequency Causes Effects Prevention 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Neurological SciencesUniversity of Vermont College of MedicineBurlingtonUSA
  2. 2.Department of NeurologyMayo ClinicRochesterUSA

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