Risk Stratification of Medulloblastoma: A Paradigm for Future Childhood Brain Tumor Management Strategies
- Roger J. Packer
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Of significant importance.
Brain tumors remain one of the most challenging forms of malignancies to effectively treat. Embryonal tumors are the most common form of malignant childhood brain tumor and, of the embryonal tumors, the most common is medulloblastoma. Occurring predominantly in children, they may also arise in adults. Medulloblastoma, which by definition arises in the posterior fossa, has been the focus of many contemporary clinical research studies [1, 2]. It is often used as an example of a tumor that is both radiosensitive and chemosensitive and one for which sequential clinical studies have demonstrated an apparent improvement in overall survival. As more children and, for that matter, young adults with medulloblastoma survive, it has become apparent that survivors face a host of severe sequelae interfer
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- Risk Stratification of Medulloblastoma: A Paradigm for Future Childhood Brain Tumor Management Strategies
Current Neurology and Neuroscience Reports
Volume 11, Issue 2 , pp 124-126
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- Current Science Inc.
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- Roger J. Packer (1)
- Author Affiliations
- 1. Center for Neuroscience and Behavioral Medicine, Gilbert Neurofibromatosis Institute, Brain Tumor Institute, Children’s National Medical Center, 111 Michigan Avenue, NW, Washington, DC, 20010, USA