Current Neurology and Neuroscience Reports

, Volume 10, Issue 2, pp 127–132

New Daily Persistent Headache in Children and Adolescents


DOI: 10.1007/s11910-010-0097-3

Cite this article as:
Baron, E.P. & Rothner, A.D. Curr Neurol Neurosci Rep (2010) 10: 127. doi:10.1007/s11910-010-0097-3


New daily persistent headache (NDPH) is a form of chronic daily headache (CDH) that may have features of both migraine and tension-type headache. In contrast with other types of CDH, NDPH is characterized by patients recalling the specific date their unremitting daily headache began. In comparison, chronic tension-type headache and chronic migraine are preceded by a gradually increasing frequency of headache. After several months, all three of these CDH forms often have a similar phenotype, making early history a key to diagnosing NDPH. Evaluations to exclude secondary causes are necessary but usually negative. NDPH is difficult to treat and requires a multimodal approach. Questions regarding NDPH remain unanswered. Additional prospective studies are necessary to further understand, characterize, diagnose, and treat NDPH.


New daily persistent headacheChronic daily headacheChildrenAdolescentsChronic migraineChronic tension-type headache

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Department of Neurology, Center for Headache and Pain/T33Cleveland Clinic Neurological InstituteClevelandUSA
  2. 2.Center for Pediatric Neurology/S60Cleveland Clinic Neurological InstituteClevelandUSA