Current Infectious Disease Reports

, Volume 15, Issue 6, pp 536–543

Endemic Mycoses in Immunocompromised Hosts

Authors

  • Trent R. Malcolm
    • Johns Hopkins University School of Medicine
    • Transplant and Immunocompromised Host Infectious Disease Program, Department of MedicineUniversity of California, San Francisco (UCSF)
    • UCSF
Transplant Oncology (M Ison and N Theodoropoulos, Section Editors)

DOI: 10.1007/s11908-013-0387-4

Cite this article as:
Malcolm, T.R. & Chin-Hong, P.V. Curr Infect Dis Rep (2013) 15: 536. doi:10.1007/s11908-013-0387-4

Abstract

Endemic mycoses remain a significant cause of morbidity and mortality among immunocompromised patients. As the number of immunosuppressed individuals increases worldwide, the incidence of endemic mycoses is also expected to rise. In immunocompromised patients, endemic mycoses can present in atypical fashion, cause more severe and/or disseminated disease, and result in higher mortality. Despite several noteworthy advances over the past decade, significant challenges remain with regard to the prevention, diagnosis, and therapy of endemic mycoses in immunocompromised hosts. This review highlights important developments related to the epidemiology, diagnosis, treatment, and prevention of commonly encountered endemic mycoses. We also discuss emerging topics, knowledge gaps, and areas of future research.

Keywords

Endemic fungiEndemic mycosesBlastomyces dermatitidisCoccidioides immitisCoccidioides posadasiiHistoplasma capsulatumParacoccidioides brasiliensisPenicillium marneffeiSporothrix schenkiiImmunocompromisedImmunosuppressed

Copyright information

© Springer Science+Business Media New York 2013