Bilukha OO, Rosenstein N. Prevention and control of meningococcal disease. Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2005;54:1–21.PubMedGoogle Scholar
Erickson L, De Wals P. Complications and sequelae of meningococcal disease in Quebec, Canada, 1990-1994. Clin Infect Dis. 1998;26:1159–64.PubMedCrossRefGoogle Scholar
MacNeil J: Epidemiology of Meningococcal Disease in Infants and Young Children. Presented at the Advisory Committee on Immunization Practices (ACIP) Meeting. Atlanta, GA; October 21, 2009.
Rosenstein NE, Perkins BA, Stephens DS, et al. The changing epidemiology of meningococcal disease in the United States, 1992-1996. J Infect Dis. 1999;180:1894–901.PubMedCrossRefGoogle Scholar
•• Cohn AC, MacNeil JR, Harrison LH, et al.: Changes in Neisseria meningitidis disease epidemiology in the United States, 1998-2007: implications for prevention of meningococcal disease. Clin Infect Dis 2010;50:184-91. This paper describes recent epidemiologic features of meningococcal disease in the United States, before and during implementation of the adolescent quadrivalent meningococcal conjugate vaccination program.
•• Campbell H, Borrow R, Salisbury D, Miller E: Meningococcal C conjugate vaccine: The experience in England and Wales. Vaccine 2009;27S:B20-B29. This paper reviews the experiences in England and Wales in implementing a meningococcal C conjugate vaccine program and describes surveillance data and impact of vaccination on disease.
Smith I, Caugant DA, Hoiby EA, et al. High case-fatality rates of meningococcal disease in Western Norway caused by serogroup C strains belonging to both sequence type (ST)-32 and ST-11 complexes, 1985-2002. Epidemiol Infect. 2006;134:1195–202.PubMedCrossRefGoogle Scholar
Trotter CL, Ramsay ME. Vaccination against meningococcal disease in Europe: review and recommendations for the use of conjugate vaccines. FEMS Microbiol Rev. 2007;31:101–7.PubMedCrossRefGoogle Scholar
White CP, Scott J. Meningococcal serogroup C conjugate vaccination in Canada: how far have we progressed? How far do we have to go? Can J Public Health. 2010;101:12–4.PubMedGoogle Scholar
Trotter CL, Chandra M, Cano R, et al. A surveillance network for meningococcal disease in Europe. FEMS Microbiol Rev. 2007;31:27–36.PubMedCrossRefGoogle Scholar
Deghmane AE, Parent du Chatelet I, Szatanik M, et al. Emergence of new virulent Neisseria meningitidis serogroup C sequence type 11 isolates in France. J Infect Dis. 2010;202:247–50.PubMedCrossRefGoogle Scholar
Khatami A, Pollard AJ. The epidemiology of meningococcal disease and the impact of vaccines. Expert Rev Vaccines. 2010;9:285–98.PubMedCrossRefGoogle Scholar
Cohn A: Optimizing the Adolescent Meningococcal Vaccination Program. Presented at the Advisory Committee on Immunization Practices (ACIP) Meeting. Atlanta, GA; October 27, 2010.
CDC: Updated Recommendations for Use of Meningococcal Conjugate Vaccines––Advisory Committee on Immunization Practices (ACIP), 2010. MMWR 2011;60(3):72–76.
European Centre for Disease Prevention and Control. Available at http://ecdpc.europa.eu/Activities/surveillance/EU_IBIS/index.html
. Accessed December 2010.
Clark TA, Stern EJ, Pondo T, et al.: The effect of quadrivalent (A, C, Y, W-135) meningococcal conjugate vaccine on serogroup-specific carriage of Neisseria meningitidis [Abstract O52]. Presented at the 16th International Pathogenic Neisseria Conference. Rotterdam, The Netherlands; September 7-12, 2008.
Goldschneider I, Gotschlich EC, Artenstein MS. Human immunity to the meningococcus. II. Development of natural immunity. J Exp Med. 1969;129:1327–48.PubMedCrossRefGoogle Scholar
Reller BL, MacGregor RR, Beaty HN. Bactericidal antibody after colonization with Neisseria meningitidis. J Infect Dis. 1973;127:56–62.PubMedCrossRefGoogle Scholar
Gold R, Goldschneider L, Lepow ML, et al. Carriage of Neisseria meningitidis and Neisseria lactamica in infants and children. J Infect Dis. 1978;137:112–21.PubMedCrossRefGoogle Scholar
Zorgani AA, James VS, Stewart J, et al. Serum bactericidal activity in a secondary school population following an outbreak of meningococcal disease: effects of carriage and secretor status. FEMS Immunol Med Microbiol. 1996;14:73–81.PubMedCrossRefGoogle Scholar
Aycock WL, Mueller JH. Meningococcus carrier rates and meningitis incidence. Bacteriol Rev. 1950;14:115–60.PubMedGoogle Scholar
• Lo H, Tang CM, Exley RM: Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development. Lancet Infect Dis 2009;9:418-27. This is a nice primer of innate and adaptive immune responses to the meningococcus, providing a gene-by-gene description of the pathogen’s defenses against each, and including a discussion of the inherent complications for vaccine development
Omer H, Rose G, Jolley KA, et al. Genotypic and phenotypic modifications of neisseria meningitidis after an accidental human passage. PLoS One. 2011;6:e17145.PubMedCrossRefGoogle Scholar
Swartley JS, Marfin AA, Edupuganti S, et al. Capsule switching of Neisseria meningitidis. Proc Natl Acad Sci U S A. 1997;94:271–6.PubMedCrossRefGoogle Scholar
Harrison LH, Shutt KA, Schmink SE, et al. Population structure and capsular switching of invasive Neisseria meningitidis isolates in the pre-meningococcal conjugate vaccine era–United States, 2000–2005. J Infect Dis. 2010;201:1208–24.PubMedCrossRefGoogle Scholar
Simoes MJ, Cunha M, Almeida F, et al. Molecular surveillance of Neisseria meningitidis capsular switching in Portugal, 2002-2006. Epidemiol Infect. 2009;137:161–5.PubMedCrossRefGoogle Scholar
Beddek AJ, Li MS, Kroll JS, et al. Evidence for capsule switching between carried and disease-causing Neisseria meningitidis strains. Infect Immun. 2009;77:2989–94.PubMedCrossRefGoogle Scholar
Marri PR, Paniscus M, Weyand NJ, et al. Genome sequencing reveals widespread virulence gene exchange among human Neisseria species. PLoS One. 2010;5:e11835.PubMedCrossRefGoogle Scholar
Snyder L, Marri PR, Weyand N, So M: The division and cell wall synthesis clusters of the commensal Neisseria spp. [abstract P075]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Wu HM, Harcourt BH, Hatcher CP, et al. Emergence of ciprofloxacin-resistant Neisseria meningitidis in North America. N Engl J Med. 2009;360:886–92.PubMedCrossRefGoogle Scholar
•• Uria MJ, Zhang Q, Li Y, et al.: A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodies. J Exp Med 2008;205:1423-34. This paper reports the discovery of the effects on capsule expression of IS1301 in the ctr-sia intergenic region
Kugelberg E, Gollan B, Farrance C, et al. The influence of IS1301 in the capsule biosynthesis locus on meningococcal carriage and disease. PLoS One. 2010;5:e9413.PubMedCrossRefGoogle Scholar
Tribe DE, Zaia AM, Griffith JM, et al. Increase in meningococcal disease associated with the emergence of a novel ST-11 variant of serogroup C Neisseria meningitidis in Victoria, Australia, 1999-2000. Epidemiol Infect. 2002;128:7–14.PubMedCrossRefGoogle Scholar
Martin SL, Borrow R, van der Ley P, et al. Effect of sequence variation in meningococcal PorA outer membrane protein on the effectiveness of a hexavalent PorA outer membrane vesicle vaccine. Vaccine. 2000;18:2476–81.PubMedCrossRefGoogle Scholar
Rosenqvist E, Hoiby EA, Wedege E, et al. A new variant of serosubtype P1.16 in Neisseria meningitidis from Norway, associated with increased resistance to antibodies induced by a serogroup B outer membrane protein vaccine. Microb Pathog. 1993;15:197–205.PubMedCrossRefGoogle Scholar
Taha MK, Bichier E, Perrocheau A, Alonso JM. Circumvention of herd immunity during an outbreak of meningococcal disease could be correlated to escape mutation in the porA gene of Neisseria meningitidis. Infect Immun. 2001;69:1971–3.PubMedCrossRefGoogle Scholar
Tsang RS, Tsai CM, Zhu P, et al. Phenotypic and genetic characterization of a unique variant of serogroup C ET-15 meningococci (with the antigenic formula C:2a:P1.7,1) causing invasive meningococcal disease in Quebec, Canada. J Clin Microbiol. 2004;42:1460–5.PubMedCrossRefGoogle Scholar
Weinberger DM, Malley R, Lipsitch M: Serotype replacement in disease after pneumococcal vaccination. Lancet 2011; In Press
Lipstich M. Bacterial vaccines and serotype replacement: lessons from Haemophilus influenza and prospects for Streptococcus pneumoniae. Emerg Infect Dis. 1999;5(3):336–45.CrossRefGoogle Scholar
Jiang HQ, Hoiseth SK, Harris SL, et al. Broad vaccine coverage predicted for a bivalent recombinant factor H binding protein based vaccine to prevent serogroup B meningococcal disease. Vaccine. 2010;28:6086–93.PubMedCrossRefGoogle Scholar
Donnelly J, Medini D, Boccadifuoco G, et al. Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines. Proc Natl Acad Sci U S A. 2010;107:19490–5.PubMedCrossRefGoogle Scholar
Harris SL, Zhu D, Murphy E, et al.: Preclinical evidence for the potential of a bivalent fHBP vaccine to prevent Neisseria meningitidis Serogroup C Disease. Hum Vaccin 2011;7.
Beernink PT, Caugant DA, Welsch JA, et al. Meningococcal factor H-binding protein variants expressed by epidemic capsular group A, W135, and X strains from Africa. J Infect Dis. 2009;199:1360–8.PubMedCrossRefGoogle Scholar
Cohn AC, Wang X, MacNeil JR, et al.: Potential impact of serogroup B vaccines: Prevalence of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States [abstract OE35]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Murphy E, Lubomira A, Flint M, et al.: Prevalence of factor H binding protein (fHBP) variants in N. meningitidis carriage isolates [abstract P037]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Holst J, Bambine S, Muzzi A, et al.: Sequence variation and degree of expression for five genome-derived vaccine antigens included in the MenB Novartis investigational vaccine [abstract P047]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Wang X, Cohn A, Comanducci M, et al.: Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States [abstract P089]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Hadad R, Jacobsson S, Pizza M, et al.: Meningococcal 5CVMB vaccine antigens – prevalence and polymorphisms of the encoding genes in Neisseria gonorrhoeae [abstract P210]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Marsh JW, O’Leary MM, Shutt KA, et al.: Diversity of neisserial heparin binding antigen in US carriage isolates [abstract P226]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Marsh JW, Shutt KA, O’Leary MM, et al.: Sequence diversity of factor-H binding protein in US carriage isolates [abstract P228]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Anderson AS, Zhu D, Wang X, et al.: Effectiveness of a bivalent factor H binding protein vaccine across Neisseria meningitidis serogroups [abstract P237]. Presented at the 17th International Pathogenic Neisseria Conference. Banff, Canada; September 11-16, 2010.
Ala’aldeen DA, Flint M, Oldfield NJ, et al. Human antibody responses to the meningococcal factor H binding protein (LP2086) during invasive disease, colonization and carriage. Vaccine. 2010;28:7667–75.PubMedCrossRefGoogle Scholar