Current Infectious Disease Reports

, Volume 7, Issue 4, pp 299-308

First online:

Update on hepatitis B and C coinfection in HIV

  • Patrick Yachimski
  • , Raymond T. ChungAffiliated withGRJ 825, GI Unit, Massachusetts General Hospital

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Coinfection with hepatitis B virus (HBV) or hepatitis C virus (HCV) is common in patients with HIV infection. HIV infection and immunosuppression alter the natural history of chronic viral hepatitis, and some patients experience accelerated progression to clinically significant liver disease. Therapies used in the treatment of HBV or HCV monoinfection have been applied to the treatment of HIV-coinfected patients. However, development of viral resistance and lack of virologic response remain significant areas of concern. Timely diagnosis and clinical staging of chronic hepatitis infection are critical in the management of HIV-coinfected patients.