Current Infectious Disease Reports

, Volume 4, Issue 4, pp 285-292

First online:

Cardiac transplantation: Pre-transplant infectious diseases evaluation and post-transplant prophylaxis

  • Susan KeayAffiliated withDivision of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine and Medical Service, VA Maryland Health Care System

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Screening of recipients and donors of cardiac allografts for infectious pathogens, and the use of appropriate immunization and antimicrobial prophylaxis strategies, remain important for the control of infection following heart transplantation. However, the risk of infectious complications in a particular patient must often be weighed against the risk of delaying or denying allograft transplantation. In addition, the ongoing degree of immunosuppression and its contribution to the risk for infectious complications should also be considered to guide the length of prophylactic antimicrobial therapy and provide optimal patient care.