Current Hypertension Reports

, 16:475

Maternal Preeclampsia and Risk for Cardiovascular Disease in Offspring

Preeclampsia (VD Garovic, Section Editor)

DOI: 10.1007/s11906-014-0475-3

Cite this article as:
Herrera-Garcia, G. & Contag, S. Curr Hypertens Rep (2014) 16: 475. doi:10.1007/s11906-014-0475-3
Part of the following topical collections:
  1. Topical Collection on Preeclampsia

Abstract

Hypertensive disease of pregnancy (HDP) has been associated with elevated lifetime cardiovascular risk, including stroke, myocardial disease, coronary artery disease, and peripheral arterial disease. These two entities share common risk factors such as obesity, insulin resistance, diabetes, and hypertension. This article will evaluate the current literature on the maternal and fetal cardiovascular risks posed by HDP. The landmark study by Barker et al. demonstrated increased cardiovascular risk in growth-restricted infants, which may also be associated with HDP. Research has demonstrated the effects that HDP may have on the vascular and nephron development in offspring, particularly with respect to endothelial and inflammatory markers. In order to control for confounding variables and better understand the relationship between HDP and lifetime cardiovascular risk, future research will require following blood pressure and metabolic profiles of the parturients and their offspring.

Keywords

Cardiovascular disease Preeclampsia Gestational hypertension Offspring Cardiovascular risk Hypertensive disease in pregnancy Metabolic syndrome 

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Obstetrics and Gynecology DepartmentSinai HospitalBaltimoreUSA
  2. 2.The Institute for Maternal-Fetal Medicine, The Louis and Henrietta Blaustein Women’s Health CenterSinai HospitalBaltimoreUSA