Current Hypertension Reports

, Volume 13, Issue 6, pp 456–464

Does Sustained Weight Loss Reverse the Metabolic Syndrome?

Special Situations in the Management of Hypertension (Theodore Kotchen, Section Editor)

DOI: 10.1007/s11906-011-0221-z

Cite this article as:
Ferland, A. & Eckel, R.H. Curr Hypertens Rep (2011) 13: 456. doi:10.1007/s11906-011-0221-z


The prevalence of the metabolic syndrome (MetS) has increased rapidly in North America in recent years. Presently, the MetS is found in 34.3% of the population, and the prevalence is likely to continue to increase in parallel with the obesity epidemic. Losing weight and long-term maintenance of the weight loss are primary targets to beneficially reverse all of the components of the MetS. This paper reviews the clinical and experimental evidence for the reversal of the metabolic complications related to the MetS that follows a sustained weight loss.


Metabolic syndrome Weight loss Weight maintenance Lifestyle intervention Abdominal obesity Hypertension Lipids Lipoproteins Hyperglycemia Insulin resistance Diet Anti-obesity drugs Bariatric surgery 

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Division of Endocrinology, Metabolism and Diabetes, MS 8106University of Colorado Anschutz Medical CampusAuroraUSA

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