Current Hypertension Reports

, Volume 13, Issue 3, pp 244–248

Stress and Its Role in Sympathetic Nervous System Activation in Hypertension and the Metabolic Syndrome


DOI: 10.1007/s11906-011-0186-y

Cite this article as:
Lambert, E.A. & Lambert, G.W. Curr Hypertens Rep (2011) 13: 244. doi:10.1007/s11906-011-0186-y


Stress in several guises is evident in individuals with hypertension and in those with the metabolic syndrome and may account, at least in part, for the extent and pattern of sympathetic nervous activation. Importantly, elevated activity of the sympathetic nervous system is related to the development of obesity-related illnesses including hypertension, insulin resistance, and renal, cardiac, and vascular impairment. Notably, evidence of subclinical organ damage is evident even in young, normotensive, overweight persons, thereby reinforcing the need to develop and implement effective early intervention.


StressSympathetic nervous systemObesityMetabolic syndrome

Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  1. 1.Human Neurotransmitters LaboratoryBaker IDI Heart & Diabetes InstituteMelbourneAustralia