, Volume 10, Issue 1, pp 1-2

HIV: So Near and Yet So Far

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Advances in HIV medicine in the past decade have transformed a once deadly infection into a chronic disease. HIV-infected individuals on potent antiretroviral treatment (ART) in both developed [1] and developing settings [2] can expect to live a near-normal lifespan. Both the incidence and deaths attributed to HIV infection have declined over the past 10 years. However, despite these amazing developments, enormous challenges remain. Access to care is far from ideal in many settings. HIV-positive persons on virally suppressive ART are at higher risk of non-AIDS-related morbidities such as myocardial infarctions, strokes, osteopenia, liver disease and non-AIDS malignancies [3, 4]. Two and a half million people continue to get infected every year [5]. The holy grails of HIV research – a cure and a vaccine – remain elusive but not impossible goals. For the first time, the idea of ending the AIDS epidemic has entered the realm of the possible.

HIV-infected individuals on ART are at a higher