Combination HIV Prevention: Significance, Challenges, and Opportunities
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No single HIV prevention strategy will be sufficient to control the HIV pandemic. However, a growing number of interventions have shown promise in partially protecting against HIV transmission and acquisition, including knowledge of HIV serostatus, behavioral risk reduction, condoms, male circumcision, needle exchange, treatment of curable sexually transmitted infections, and use of systemic and topical antiretroviral medications by both HIV-infected and uninfected persons. Designing the optimal package of interventions that matches the epidemiologic profile of a target population, delivering that package at the population level, and evaluating safety, acceptability, coverage, and effectiveness, all involve methodological challenges. Nonetheless, there is an unprecedented opportunity to develop “prevention packages” that combine various arrays of evidence-based strategies, tailored to the needs of diverse subgroups and targeted to achieve high coverage for a measurable reduction in population-level HIV transmission. HIV prevention strategies that combine partially effective interventions should be scaled up and evaluated.
Supplementary Material (0)
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About this Article
- Combination HIV Prevention: Significance, Challenges, and Opportunities
Current HIV/AIDS Reports
Volume 8, Issue 1 , pp 62-72
- Cover Date
- Print ISSN
- Online ISSN
- Current Science Inc.
- Additional Links
- Combination HIV prevention
- HIV prevention methods
- HIV prevention packages
- Antiretroviral therapy
- Test and treat
- Author Affiliations
- 1. New York University College of Nursing, 726 Broadway, 10th floor, New York, NY, 10003, USA
- 3. Department of Global Health, University of Washington, Seattle, WA, USA
- 2. Department of Medicine, University of Washington, Seattle, WA, USA
- 4. Vanderbilt Institute for Global Health, Vanderbilt University School of Medicine, Nashville, TN, USA
- 5. Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN, USA