Current HIV/AIDS Reports

, Volume 7, Issue 4, pp 194–200

Increasing and Supporting the Participation of Persons of Color Living with HIV/AIDS in AIDS Clinical Trials

  • Marya Viorst Gwadz
  • Pablo Colon
  • Amanda S. Ritchie
  • Noelle R. Leonard
  • Charles M. Cleland
  • Marion Riedel
  • DeShannon Bowens
  • Angela D. Banfield
  • Patricia Chang
  • Robert Quiles
  • Donna Mildvan
Article

DOI: 10.1007/s11904-010-0055-3

Cite this article as:
Gwadz, M.V., Colon, P., Ritchie, A.S. et al. Curr HIV/AIDS Rep (2010) 7: 194. doi:10.1007/s11904-010-0055-3

Abstract

Persons living with HIV/AIDS (PLHA) of color are under-represented in AIDS clinical trials (ACTs), which may limit the generalizability of research findings and denies many individuals access to high levels of care and new treatments available through ACTs. Disproportionately low rates of recruitment in health care settings and by providers are a major barrier to ACTs for this group. Moreover, PLHA of color are more likely than their white peers to decline to participate, mainly due to fear and mistrust (although willingness is also high), negative social norms about ACTs, and difficulty navigating the unfamiliar ACT system. We describe a small number of successful behavioral and structural interventions to increase the participation of PLHA of color in screening for and enrollment into ACTs. HIV care settings, clinical trials sites, and trial sponsors are uniquely positioned to develop procedures, supports, and trials to increase the proportion of PLHA of color in ACTs.

Keywords

Clinical trials HIV/AIDS Racial/ethnic disparities African-American Latino Access 

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Marya Viorst Gwadz
    • 1
  • Pablo Colon
    • 1
  • Amanda S. Ritchie
    • 1
  • Noelle R. Leonard
    • 1
  • Charles M. Cleland
    • 2
  • Marion Riedel
    • 3
  • DeShannon Bowens
    • 4
  • Angela D. Banfield
    • 1
  • Patricia Chang
    • 1
  • Robert Quiles
    • 1
  • Donna Mildvan
    • 5
  1. 1.New York University College of NursingNew YorkUSA
  2. 2.National Development and Research Institutes, Inc (NDRI)New YorkUSA
  3. 3.Columbia University School of Social WorkNew YorkUSA
  4. 4.ILERA Counseling & Education ServiceYonkersUSA
  5. 5.Division of Infectious Diseases, Beth Israel Medical CenterNew YorkUSA

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