Current Heart Failure Reports

, Volume 6, Issue 3, pp 182–190

Nitroprusside in decompensated heart failure: What should a clinician really know?

  • Cristina Opasich
  • Giovanni Cioffi
  • Alessandra Gualco

DOI: 10.1007/s11897-009-0026-4

Cite this article as:
Opasich, C., Cioffi, G. & Gualco, A. Curr Heart Fail Rep (2009) 6: 182. doi:10.1007/s11897-009-0026-4


Sodium nitroprusside is an older intravenous vasodilator appropriate for acute hospital treatment of patients with congestive heart failure. It is a balanced arterial and venous vasodilator with a very short half-life, facilitating rapid titration. In general, it improves hemodynamic and clinical status by reducing systemic vascular resistance, left ventricular filling pressure, and increasing cardiac output. This review summarizes recently published literature and recent data regarding the use of this intravenous vasodilator in decompensated heart failure patients.

Copyright information

© Current Medicine Group, LLC 2009

Authors and Affiliations

  • Cristina Opasich
    • 1
  • Giovanni Cioffi
  • Alessandra Gualco
  1. 1.Division of CardiologySalvatore Maugeri FoundationPaviaItaly