Current Gastroenterology Reports

, Volume 13, Issue 2, pp 140-149

Recurrent and Relapsing Pancreatitis

  • Nalini M. GudaAffiliated withUniversity of Wisconsin School of Medicine and Public Health, St. Luke’s Medical Center Email author 
  • , Joseph RomagnuoloAffiliated withDivision of Gastroenterology and Hepatology, Digestive Disease Center, Medical University of South Carolina
  • , Martin L. FreemanAffiliated withDivision of Gastroenterology, Hepatology and Nutrition, University of MinnesotaTotal Pancreatectomy and Islet Autotransplantation, University of MinnesotaPancreaticobiliary Endoscopy Fellowship, University of MinnesotaAmerican Pancreatic Association, University of Minnesota

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Recurrent acute pancreatitis is a common clinical problem. Most cases of pancreatitis are identified by a careful history and physical examination. Despite advanced evaluation, the cause is not apparent in about 10% of cases. The etiology of recurrent acute pancreatitis appears to be multifactorial, with genetic and environmental influences playing a significant role. The strength of evidence for certain etiologies is highly variable, and natural history data are limited. Controversy exists regarding the most appropriate diagnostic and therapeutic approach. Recurrent acute pancreatitis often represents a continuum with chronic pancreatitis.


Pancreatitis Recurrent acute pancreatitis Idiopathic pancreatitis Endoscopic retrograde cholangiopancreatography Endoscopic ultrasound Magnetic resonance cholangiopancreatography