Current Gastroenterology Reports

, Volume 12, Issue 4, pp 288–295

Micronutrient-Related Neurologic Complications Following Bariatric Surgery

Article

DOI: 10.1007/s11894-010-0120-5

Cite this article as:
Kazemi, A., Frazier, T. & Cave, M. Curr Gastroenterol Rep (2010) 12: 288. doi:10.1007/s11894-010-0120-5

Abstract

Nearly two thirds of American adults are either overweight or obese. Accordingly, bariatric surgery experienced explosive growth during the past decade. Current estimates place the worldwide volume of bariatric procedures at greater than 300,000 cases annually. Micronutrient deficiencies are well-described following bariatric surgery, and they may present with devastating and sometimes irreversible neurologic manifestations. Clinical symptoms range from peripheral neuropathy to encephalopathy, and are most commonly caused by thiamine, copper, and B12 deficiencies.

Keywords

Bariatric surgeryRoux-en-Y gastric bypassLap-bandVitamin deficiencyWernicke’s encephalopathyThiamineCopperVitamin B12Acute post-gastric reduction surgery (APGARS) neuropathy

Abbreviations

BMI

Body mass index

APGARS neuropathy

Acute post-gastric reduction surgery neuropathy

MRI

Magnetic resonance imaging

RDA

Recommended daily allowance

WE

Wernicke’s encephalopathy

KS

Korsakoff’s syndrome

cyanoCbl

cyanocobalamin

IF-cyanoCbl complex

Intrinsic factor-cyanocobalamin complex

methylCbl

methylcobalamin

MethylTHF

methyltetrahydrofolate

Copyright information

© US Government 2010

Authors and Affiliations

  1. 1.Department of MedicineUniversity of LouisvilleLouisvilleUSA
  2. 2.Division of Gastroenterology, Hepatology, and NutritionUniversity of LouisvilleLouisvilleUSA
  3. 3.Department of Pharmacology and ToxicologyUniversity of LouisvilleLouisvilleUSA
  4. 4.The Louisville Veterans Affairs Medical CenterLouisvilleUSA
  5. 5.University of LouisvilleLouisvilleUSA
  6. 6.Department of Internal MedicineUniversity of Louisville Medical CenterLouisvilleUSA