Current Gastroenterology Reports

, Volume 9, Issue 5, pp 385–392

Commensal bacteria and epithelial cross talk in the developing intestine


DOI: 10.1007/s11894-007-0047-7

Cite this article as:
Rautava, S. & Walker, W.A. Curr Gastroenterol Rep (2007) 9: 385. doi:10.1007/s11894-007-0047-7


Indigenous intestinal microbes have co-evolved with the intestinal immune system to form a symbiotic ecosystem. In the postnatal period, intestinal microbes provide the developing gut with stimuli that are necessary for healthy maturation of the intestinal immune system. Cross talk between the host and commensal microbes is an essential component of gut homeostasis mechanisms also in later life. During recent years, innovative research has shed light on the molecular mechanisms of these interactions.

Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  1. 1.Mucosal Immunology LaboratoryMassachusetts General HospitalCharlestownUSA

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