Current Gastroenterology Reports

, Volume 6, Issue 1, pp 37–43

Hepatocellular carcinoma: Updates in primary prevention

  • Will J. FechtJr
  • Alex S. Befeler

DOI: 10.1007/s11894-004-0024-3

Cite this article as:
Fecht, W.J. & Befeler, A.S. Curr Gastroenterol Rep (2004) 6: 37. doi:10.1007/s11894-004-0024-3


Hepatocellular carcinoma is a significant cause of mortality worldwide and a growing problem in the United States. Treatment options are often limited, and median survival is less than 1 year. Thus, prevention may provide the best opportunity to alter the natural history of this disease. Primary prevention is best exemplified by the successes of such public health measures as universal hepatitis B vaccination. Such antiviral therapies as interferon may also have a role. Lessons can be learned from complementary and alternative medicine. Nevertheless, more work is needed in understanding hepatocarcinogenesis and in developing models to assess potential chemopreventive agents.

Copyright information

© Current Science Inc 2004

Authors and Affiliations

  • Will J. FechtJr
    • 1
  • Alex S. Befeler
    • 1
  1. 1.Division of Gastroenterology and HepatologySaint Louis University School of MedicineSt. LouisUSA

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