Current Gastroenterology Reports

, Volume 2, Issue 4, pp 299–304

Toward a new understanding of Whipple’s disease

  • Mark C. Flemmer
  • Ronald W. Flenner

DOI: 10.1007/s11894-000-0022-z

Cite this article as:
Flemmer, M.C. & Flenner, R.W. Curr Gastroenterol Rep (2000) 2: 299. doi:10.1007/s11894-000-0022-z


Since the first successful antibiotic treatment of Whipple’s disease in 1952, many breakthroughs have occurred in the diagnosis and treatment of this disease that was once thought fatal. This article provides a historic overview and highlights recent encouraging discoveries regarding this underdiagnosed disease, including the use of polymerase chain reaction techniques and the recent cultivation of the Tropheryma whippelii bacterium.

Copyright information

© Current Science Inc. 2000

Authors and Affiliations

  • Mark C. Flemmer
    • 1
  • Ronald W. Flenner
    • 1
  1. 1.Department of Internal MedicineEastern Virginia Medical SchoolNorfolkUSA