Current Diabetes Reports

, 16:93

Diet and Gut Microbial Function in Metabolic and Cardiovascular Disease Risk

Lifestyle Management to Reduce Diabetes/Cardiovascular Risk (C Shay and B Conway, Section Editors)

DOI: 10.1007/s11892-016-0791-x

Cite this article as:
Meyer, K.A. & Bennett, B.J. Curr Diab Rep (2016) 16: 93. doi:10.1007/s11892-016-0791-x
Part of the following topical collections:
  1. Topical Collection on Lifestyle Management to Reduce Diabetes/Cardiovascular Risk


Over the past decade, the gut microbiome has emerged as a novel and largely unexplored source of variability for metabolic and cardiovascular disease risk, including diabetes. Animal and human studies support several possible pathways through which the gut microbiome may impact health, including the production of health-related metabolites from dietary sources. Diet is considered important to shaping the gut microbiota; in addition, gut microbiota influence the metabolism of many dietary components. In the present paper, we address the distinction between compositional and functional analysis of the gut microbiota. We focus on literature that highlights the value of moving beyond surveys of microbial composition to measuring gut microbial functioning to delineate mechanisms related to the interplay between diet and gut microbiota in cardiometabolic health.


Gut microbiota Metabolites Nutrition Diabetes Cardiovascular disease 

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Department of Nutrition, Gillings School of Global Public HealthUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Nutrition Research InstituteUniversity of North Carolina at Chapel HillKannapolisUSA
  3. 3.Department of Genetics, School of MedicineUniversity of North Carolina at Chapel HillChapel HillUSA

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