Current Diabetes Reports

, Volume 9, Issue 4, pp 312–316

History of islet transplantation


DOI: 10.1007/s11892-009-0048-z

Cite this article as:
Digon, B.J. Curr Diab Rep (2009) 9: 312. doi:10.1007/s11892-009-0048-z


Patients with a diagnosis of type 1 diabetes mellitus endure stringent life-long medical therapy through the use of insulin to prevent end organ complications and maintain normoglycemia. However, some patients still suffer from hypoglycemic unawareness, even under intensive therapy. Within the past decade, noble efforts have been attempted to provide normoglycemia through cadaveric islet of Langerhans transplantation in order to reach a physiologic response. This effort, which has evolved for more than a century, actually predates the discovery of insulin.

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© Current Medicine Group, LLC 2009

Authors and Affiliations

  1. 1.The Endocrinology CenterHalifax Health Medical CenterDaytona BeachUSA