NASH and the risk of cirrhosis and hepatocellular carcinoma in type 2 diabetes
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- Bugianesi, E., Vanni, E. & Marchesini, G. Curr Diab Rep (2007) 7: 175. doi:10.1007/s11892-007-0029-z
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The risk of chronic liver disease and liver-related mortality is increased in patients with type 2 diabetes mellitus. Several cohort studies have suggested a metabolic pathway from nonalcoholic fatty liver, nonalcoholic steatohepatitis, cryptogenic cirrhosis, and eventually hepatocellular carcinoma. Although cardiovascular risk remains the major cause for excess mortality in type 2 diabetes mellitus, the risk of progressive liver disease should no longer be underscored.