Current Diabetes Reports

, Volume 7, Issue 3, pp 175–180

NASH and the risk of cirrhosis and hepatocellular carcinoma in type 2 diabetes

  • Elisabetta Bugianesi
  • Ester Vanni
  • Giulio Marchesini

DOI: 10.1007/s11892-007-0029-z

Cite this article as:
Bugianesi, E., Vanni, E. & Marchesini, G. Curr Diab Rep (2007) 7: 175. doi:10.1007/s11892-007-0029-z


The risk of chronic liver disease and liver-related mortality is increased in patients with type 2 diabetes mellitus. Several cohort studies have suggested a metabolic pathway from nonalcoholic fatty liver, nonalcoholic steatohepatitis, cryptogenic cirrhosis, and eventually hepatocellular carcinoma. Although cardiovascular risk remains the major cause for excess mortality in type 2 diabetes mellitus, the risk of progressive liver disease should no longer be underscored.

Copyright information

© Current Medicine Group LLC 2007

Authors and Affiliations

  • Elisabetta Bugianesi
    • 1
  • Ester Vanni
  • Giulio Marchesini
  1. 1.Division of Gastro-HepatologyUniversity of Turin, S. Giovanni Battista HospitalTurinItaly