Lessons for human diabetes from experimental mouse models
- Cite this article as:
- Kulkarni, R.N. & Zisman, A. Curr Diab Rep (2003) 3: 168. doi:10.1007/s11892-003-0041-x
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A precise knowledge of the defects underlying type 1 and type 2 diabetes is essential for designing appropriate therapeutic strategies. Because experiments in humans are limited, naturally occurring, and especially genetically engineered rodent models, have revolutionized research in diabetes. We review some of the models created recently and discuss their impact on human diabetes.