The Continuum of Care in Chemotherapy Approach to Metastatic Colorectal Cancer
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- Jenab-Wolcott, J. & Giantonio, B. Curr Colorectal Cancer Rep (2013) 9: 230. doi:10.1007/s11888-013-0178-1
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Colorectal cancer is a major public health problem and, despite recent advances in treatment, most patients with metastatic colorectal cancer (mCRC) will succumb to their disease. Yet, survival of patients with mCRC has markedly improved as the number of effective cytotoxic and novel targeted agents has grown. However, the best order and combination of these agents, and the optimum duration of treatment with the purpose of maximizing efficacy while minimizing toxicity are not fully established.