Cardiovascular Effects of Anti-Diabetic Medications in Type 2 Diabetes Mellitus
Diabetes and Cardiovascular Disease (S Malik, Section Editor)
First Online: 08 December 2012 DOI:
Cite this article as: Singh, S., Bhat, J. & Wang, P.H. Curr Cardiol Rep (2013) 15: 327. doi:10.1007/s11886-012-0327-1 Abstract
Over the past several years, there have been a significant number of new agents developed for the treatment of type 2 diabetes. Our goal in this article is to review the cardiovascular effects (risks and benefits) of these oral and non-insulin injectable agents. We review six major categories of diabetic therapies: biguanides, sulfonylureas, alpha-glucosidase inhibitors, thiazolidinediones, GLP-1 agonists, and DPP-IV inhibitors. In order to achieve a personalized regimen that aims for optimal outcomes, we must take into consideration each drug’s side effects, patients’ cardiovascular risk factors, and their individual health profile.
Keywords Type 2 diabetes Medications Side effects Oral agents Heart Cardiovascular effects
This article is part of the Topical Collection on
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