Premise, Promise, and Potential Limitations of Invasive Devices to Treat Hypertension
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- Martin, E.A. & Victor, R.G. Curr Cardiol Rep (2011) 13: 86. doi:10.1007/s11886-010-0156-z
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Invasive device-based therapies for drug-resistant hypertension are undergoing active clinical investigation. The two approaches are 1) permanent implantation of a carotid baroreceptor pacemaker and 2) radiofrequency catheter ablation of the renal nerves. Both are designed to reduce the sympathetic nervous system component of drug-resistant hypertension. Several excellent comprehensive articles have reviewed each of these devices separately. In contrast, this brief article aims to provide a conceptual framework for evaluating the premise, promise, and potential limitations of both invasive antihypertensive therapies.