Current Cardiology Reports

, Volume 13, Issue 1, pp 30–37

Interventional Management of Asymptomatic Extracranial Carotid Stenosis

Authors

  • Vincent V. Truong
    • University of Louisville School of Medicine
    • Department of NeurologyUniversity of Louisville School of Medicine
Article

DOI: 10.1007/s11886-010-0155-0

Cite this article as:
Truong, V.V. & Abou-Chebl, A. Curr Cardiol Rep (2011) 13: 30. doi:10.1007/s11886-010-0155-0

Abstract

Carotid artery stenosis is a major risk factor for stroke and transient ischemic attack. Although carotid endarterectomy is the established gold standard for carotid revascularization, carotid artery angioplasty and stenting (CAS)—proven by large randomized clinical trials and rigorous registries and supported by improving stent designs, embolic protection, and increasing neurointerventionalist experience—is developing into a safer and more efficacious method of stroke prevention. Today, protected CAS is approved for symptomatic and asymptomatic patients with severe carotid stenosis with high surgical risk. We reviewed recently published data regarding new developments in the use of protected CAS, particularly in patients with carotid stenosis who are either asymptomatic or at low surgical risk.

Keywords

Extracranial carotid stentingAsymptomatic carotid stenosisSAPPHIRECRESTOngoing carotid trials

Clinical Trial Acronyms

ACAS

Asymptomatic Carotid Atherosclerosis Study

ACST

Asymptomatic Carotid Surgery Trial

ACT-1

Asymptomatic Carotid Stenosis, Stenting Versus Endarterectomy Trial

CABERNET

Carotid Artery Revascularization Using the Boston Scientific FilterWire EX/EZ and the EndoTex NexStent

CAPTURE

Carotid ACCULINK/ACCUNET Post Approval Trial to Uncover Rare Events

CaRESS

Carotid Revascularization Using Endarterectomy or Stenting Systems

CREST

Carotid Revascularization Endarterectomy Versus Stent

ECST

European Carotid Surgery Trial

EVA-3S

Endarterectomy Versus Angioplasty in Patients with Symptomatic Severe Carotid Stenosis

ICAROS

Imaging in Carotid Angioplasty and Risk of Stroke

ICSS

International Carotid Stenting Study

NASCET

North America Symptomatic Carotid Endarterectomy Trial

SAPPHIRE

Stenting and Angioplasty with Protection in Patients at High Risk for Endarterectomy

SPACE

Stent-Supported Percutaneous Angioplasty of the Carotid Artery Versus Endarterectomy

TACIT

Transatlantic Asymptomatic Carotid Intervention Trial

Copyright information

© Springer Science+Business Media, LLC 2010